1 Contributo su Rivista

1 Contributo su Rivista: [2634] Home page macrotipologia

Sfoglia

Prodotti recenti

Electron Microscopy and Multi-Omics Reveal Mitochondrial Dysfunction and Structural Remodeling in the Hearts of Elderly Mice

: Aging is a key driver of cardiac dysfunction, promoting structural remodeling, metabolic alterations, and loss of cellular resilience. In aged hearts, extracellular matrix remodeling and collagen accumulation reduce ventricular compliance, impairing both diastolic function and stress adaptability. Cardiomyocytes exhibit diminished regenerative capacity and dysregulated stress responses, with mitochondrial dysfunction emerging as a central contributor to energy imbalance, oxidative stress, a...

Optimizing selection of P2Y 12 inhibiting therapy: clopidogrel, prasugrel or ticagrelor

Introduction: Antiplatelet therapy is key for secondary prevention in patients with atherosclerotic cardiovascular disease, particularly those undergoing percutaneous coronary intervention (PCI). While aspirin has historically been the standard of care agent, oral P2Y₁₂ inhibitors - namely clopidogrel, prasugrel and ticagrelor - have emerged as key adjunctive therapies as well as treatment alternatives. Given their differing pharmacodynamic, pharmacogenomic, and safety - efficacy profiles, th...

Investigating visual search mechanisms and enhancing the diagnostic potential of the trail making test using eTMT

The Trail Making Test (TMT) is a complex task involving visual search and is widely used to assess various cognitive functions. While existing literature often emphasizes task switching, the nuances of visual search within the TMT remain debated. In this study, we developed a new digital version of the TMT, the eTMT, to more effectively analyze visual search performance dynamics. We hypothesized that critical aspects of visual search, particularly the display set-size effect, have been overlo...

News from the ROAR Lab at The Ohio State University

Minimally Invasive Mitral Valve Repair: Ten-Year Outcomes of the “Re-Lock Technique” for Complex Bileaflet Mitral Valve Disease

Scopri

Accesso al fulltext

reserved1245
no fulltext1228
open157
partially open4